Bradley Cooper and Renee Zellweger picture via Youtube
Cooper, 36, and Zelleweger, 41, met six years ago on the set of their movie Case 39. The two began dating in summer 2009 and reportedly moved in together last fall.
Although Zellweger and Cooper never officially confirmed their relationship, the pair were frequently spotted out together.
Just last week, the two were seen together where the Bridget Jones star supported the Limitless actor as he filmed an episode for Inside the Actors Studio.
According to US magazine, multiple sources have confirmed the split. However, reps for both Zellweger and Cooper had no comment as yet.