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Chelsea Handler: Angelina Jolie “Homewrecker” Rant (Video)

Chelsea Handler, the 35-year-old talk show host and friend of Jennifer Aniston, went on rant accusing Angelina Jolie of being a home wrecker during a stand-up comedy show in New Jersey over the weekend.

Host Chelsea Handler poses in the press room during the MTV Video Music Awards at NOKIA Theatre L.A. LIVE on September 12, 2010 in Los Angeles, California. (Photo by Frederick M. Brown/Getty Images)

"She's a homewrecker, she is," Handler said of Jolie, the current of love of Aniston's ex-husband Brad Pitt.

"She can rescue as many babies from as many countries as she wants to. I don't f***ing believe you. She gives interviews, 'Oh, I'm a guy's girl, I don't have a lot of female friends.' Because you're a f***ing c***, that's what you are!" the comedienne continued.

Handler, the host of E! chat show titled Chelsea Lately, and Aniston, 41, spent Thanksgiving holiday together with other female pals in the resort town of Cabo San Lucas, Mexico.

Get more detail’s on Chelsea Handler’s Angelina Jolie rant on the video below: